Cheers to Life is based on a true friendship between Lisa and Denise. Both have been through so much together and have always found a way to support one another in life. The moments that life puts before each person are the experiences on their life's journey. There are times when you question why, and yet other times you find yourself laughing at life and all it has to offer....or not. As Lisa and Denise sit catching up with each other, it's all eyes on them as two neighborhood guys try to move in on them with their smiles and funny pickup lines. The girls lift their glasses and celebrate each other as they Cheers To Life and all its insanity.